Namely, those mice showed much higher neuronal activity at night compared to the control group, despite the SCN typically showing less activity at this time. As the team notes in their research, “Neuronal excitability at night could lead to decline or mistiming of sleep-wake, hormonal, and physiological rhythms.”

Then, when those mice were given an endothelin B receptor blocker, all that late-night neural activity slowed down. So not only was the salt affecting their circadian rhythm, but the team adds that endothelin B receptor blockers (which are used to promote healthy blood pressure), could also potentially influence the circadian rhythms of people who take them.

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