{"id":1168,"date":"2021-08-15T12:04:57","date_gmt":"2021-08-15T12:04:57","guid":{"rendered":"https:\/\/ultimatehealthreport.com\/book-excerpt-autism-and-endocannabinoid-dysfunction\/"},"modified":"2021-08-15T12:04:57","modified_gmt":"2021-08-15T12:04:57","slug":"book-excerpt-autism-and-endocannabinoid-dysfunction","status":"publish","type":"post","link":"https:\/\/ultimatehealthreport.com\/book-excerpt-autism-and-endocannabinoid-dysfunction\/","title":{"rendered":"Book Excerpt: Autism and Endocannabinoid Dysfunction"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div property=\"content:encoded\">\n<p><em>This excerpt is adapted from <\/em>The Essential Guide to <span class=\"caps\">CBD<\/span><em> by the Editors of Reader\u2019s Digest and Project <span class=\"caps\">CBD<\/span>.<\/em><\/p>\n<p>The number of children diagnosed with autism spectrum disorders (<span class=\"caps\">ASD<\/span>) worldwide has tripled in the past 30 years. Now there\u2019s undeniable evidence that endocannabinoid system dysregulation is involved and that some people with <span class=\"caps\">ASD<\/span> have low endocannabinoid system tone.<\/p>\n<p>In 2019, in a review paper titled \u201cEndocannabinoid system involvement in autism spectrum disorder: An overview with potential therapeutic applications,\u201d researchers concluded: \u201cRecent evidence highlights a strong involvement of the <span class=\"caps\">EC<\/span> system in the pathophysiology of some neuropsychiatric disorders and of <span class=\"caps\">ASD<\/span>\u2026. Additionally, evidence from the literature indicates that <span class=\"caps\">CBD<\/span> may alleviate many conditions co-occurring with <span class=\"caps\">ASD<\/span>, such as seizures, gastrointestinal problems, anxiety and depression, attention deficit, and sleep problems.\u201d<sup id=\"fnref:1\">1<\/sup><\/p>\n<aside class=\"pull-right\">\n<p><span class=\"caps\">CBD<\/span> may alleviate many conditions co-occurring with autism spectrum disorder, such as seizures, gastrointestinal issues, anxiety and depression, attention deficit, and sleep problems.<\/p>\n<\/aside>\n<p>Parents seem to agree. In 2019, Israeli researchers surveyed the parents of 53 children and young adults, ages 4 to 22, who were receiving oral drops of <span class=\"caps\">CBD<\/span> oil for an average of 66 days.<sup id=\"fnref:2\">2<\/sup>\u00a0 Self-harm and rage attacks improved in nearly 68 percent, hyperactivity improved in 68 percent, 71 percent slept better, and 47 percent had less anxiety. In some cases, symptoms worsened: 24 percent seemed to become more anxious, for instance. Otherwise, the outcomes were mostly positive, and the adverse side effects, mostly changes in appetite and feeling sleepy, were mild.<\/p>\n<p>Another study published in <em>Nature<\/em> in 2019 analyzed data from 188 children with <span class=\"caps\">ASD<\/span> who were treated with medical cannabis \u2014 mostly <span class=\"caps\">CBD<\/span>-rich cannabis oil \u2014 between 2015 and 2017. After six months of treatment, just under a third of participants reported significant improvements, and more than half reported moderate improvements, according to quality of life questionnaires that measured mood and the ability to function independently.<sup id=\"fnref:3\">3<\/sup><\/p>\n<p>Of course, more research is needed to provide more concrete recommendations, but in the meantime, it\u2019s worth a conversation with a practitioner who is well-versed in <span class=\"caps\">CBD<\/span> and cannabis therapeutics. In some cases, children can have remarkable improvement with very small doses, says Bonni Goldstein, <span class=\"caps\">MD<\/span>, author of <em>Cannabis Is Medicine<\/em> and medical director of Canna-Centers, a California-based medical practice devoted to educating patients about the use of cannabis for serious and chronic medical conditions.<\/p>\n<div class=\"callout\"><\/div>\n<p>\u201cI had a patient, a little boy, come in with autism,\u201d said Goldstein, \u201cand the parents were desperate. So they tried a little bit \u2014 and I mean a really little bit of <span class=\"caps\">CBD<\/span> \u2014 before they came into my office, and they told me that after one week on that very low dose, the teacher had already noticed the child was doing better. The teacher did not know he was on <span class=\"caps\">CBD<\/span> oil. But she made like a beeline for the mom one day at the end of school and said, \u2018Okay what\u2019s going on? What\u2019s different?\u2019 At that tiny dose, like about 4 or 5 milligrams, they were seeing this incredible benefit in this child.\u201d<sup id=\"fnref:4\">4<\/sup><\/p>\n<p>On the other side of the spectrum, Dr. Goldstein also sees patients who require much higher doses, and nobody can really say why, because <span class=\"caps\">CBD<\/span> works on the cellular level and it\u2019s not easy to measure. \u201cThere\u2019s no way to tell by somebody\u2019s size or level of illness exactly what\u2019s going to fit them. You\u2019re not going to know until you try and see,\u201d she says.<\/p>\n<p>An excerpt from <em>The Essential Guide to <span class=\"caps\">CBD<\/span><\/em> by the editors of Reader\u2019s Digest <span class=\"amp\">&amp;<\/span> Project <span class=\"caps\">CBD<\/span>.\u00a0Copyright, Project <span class=\"caps\">CBD<\/span>. May not be reprinted without permission.<\/p>\n<hr\/>\n<p>\u00a0<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.projectcbd.org\/book-excerpt-autism-and-endocannabinoid-dysfunction\" target=\"_blank\" rel=\"noopener\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This excerpt is adapted from The Essential Guide to CBD by the Editors of Reader\u2019s Digest and Project CBD. The number of children diagnosed with [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1169,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"footnotes":""},"categories":[35],"tags":[],"_links":{"self":[{"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/posts\/1168"}],"collection":[{"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/comments?post=1168"}],"version-history":[{"count":0,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/posts\/1168\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/media\/1169"}],"wp:attachment":[{"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/media?parent=1168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/categories?post=1168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ultimatehealthreport.com\/wp-json\/wp\/v2\/tags?post=1168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}