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Postmenopausal Women and Endometrial Cancer <\/strong><\/p>\n\n\t\t\t\tFluctuating hormones and higher levels of estrogen can increase the risk for endometrial cancer\n\t\t\t<\/p>\n
What Is Endometrial Cancer? <\/strong><\/p>\n\n\t\t\t\tEndometrial cancer is a type of uterine cancer that develops in the inner lining of the uterus and is the most common cancer that affects a woman\u2019s reproductive system.\n\t\t\t<\/p>\n
Who Is at Risk for Endometrial Cancer? <\/strong><\/p>\n\n\t\t\t\tAnyone with a uterus can be diagnosed with endometrial cancer, but most cases are found in postmenopausal women.\n\t\t\t<\/p>\n
Why Postmenopausal Women Are High-Risk <\/strong><\/p>\n\n\t\t\t\tAlthough ovaries stop making estrogen and progesterone after menopause, estrogen is still made in fat tissue. This causes a hormone imbalance that leads to a higher risk for endometrial cancer.\n\t\t\t<\/p>\n
\n\t\t\t\tHormone therapy after menopause using estrogen alone without progesterone also increases the risk for endometrial cancer.\n\t\t\t<\/p>\n
Some Common Risk Factors <\/strong><\/p>\n\n- \n\t\t\t\tGetting your period early or late menopause\n\t\t\t\t<\/li>\n
- \n\t\t\t\tBeing overweight or having obesity\n\t\t\t\t<\/li>\n
- \n\t\t\t\tHaving metabolic syndrome, a cluster of conditions that put you at higher risk for heart disease and Type 2 diabetes\n\t\t\t\t<\/li>\n
- \n\t\t\t\tHaving conditions, such as polycystic ovary syndrome (PCOS), or taking medications, such as estrogen, that affect hormone levels\n\t\t\t\t<\/li>\n
- \n\t\t\t\tNever having been pregnant\n\t\t\t\t<\/li>\n
- \n\t\t\t\tHaving Lynch syndrome\n\t\t\t\t<\/li>\n<\/ul>\n
Did You Know? <\/strong><\/p>\n\n\t\t\t\tStarting your period before age 12 or going through menopause later in life increases the risk of endometrial cancer because of the increased exposure to estrogen.\n\t\t\t<\/p>\n
Some Common Signs & Symptoms <\/strong><\/p>\n\n- \n\t\t\t\tBleeding or spotting between periods\n\t\t\t\t<\/li>\n
- \n\t\t\t\tVaginal bleeding after menopause\n\t\t\t\t<\/li>\n
- \n\t\t\t\tPain during sex\n\t\t\t\t<\/li>\n
- \n\t\t\t\tPelvic pain or pressure\n\t\t\t\t<\/li>\n<\/ul>\n
These are not all of the symptoms of endometrial cancer and they could be caused by other conditions. These symptoms could be easily overlooked, so it is important to talk to your healthcare provider about any symptoms of concern as soon as they arise. If you experience any of these symptoms, contact your healthcare provider. <\/em><\/p>\nMethods of Diagnosis <\/strong><\/p>\n\n- \n\t\t\t\tPelvic exam \u2014 An examination where a HCP carefully feels the uterus, vagina and ovaries to check for any abnormalities\n\t\t\t\t<\/li>\n
- \n\t\t\t\tUltrasound \u2014 An exam that measures the endometrium thickness and uterus size\n\t\t\t\t<\/li>\n
- \n\t\t\t\tTissue sampling \u2014\n\t\t\t\t<\/li>\n
\n- \n\t\t\t\t\tBiopsy \u2014 A procedure that removes a small amount of tissue for examination under a microscope\n\t\t\t\t\t<\/li>\n
- \n\t\t\t\t\tHysteroscopy \u2014 The insertion of a thin, flexible tube with a light on it through the vagina so the HCP can view the lining of the uterus and take a tissue sample\n\t\t\t\t\t<\/li>\n
- \n\t\t\t\t\tDilation & curettage (D&C) \u2014 A procedure to remove tissue samples from the uterus to examine for cancer cells\n\t\t\t\t\t<\/li>\n<\/ul>\n<\/ul>\n
Treatment Options <\/strong><\/p>\n\n- \n\t\t\t\tSurgery to remove the uterus, ovaries and fallopian tubes\n\t\t\t\t<\/li>\n
- \n\t\t\t\tChemotherapy\n\t\t\t\t<\/li>\n
- \n\t\t\t\tRadiation\n\t\t\t\t<\/li>\n
- \n\t\t\t\tTargeted drug therapy\n\t\t\t\t<\/li>\n
- \n\t\t\t\tHormone therapy\n\t\t\t\t<\/li>\n
- \n\t\t\t\tImmunotherapy\n\t\t\t\t<\/li>\n<\/ul>\n
Survival Rate Disparity <\/strong><\/p>\n\n\t\t\t\tAlthough women overall have a 95% chance of surviving endometrial cancer , a study found that Black women have a 90% higher five-year mortality risk compared to white women.\n\t\t\t<\/p>\n
Anatomy of the Uterus<\/strong><\/p>\nFun Fact <\/strong><\/p>\n\n\t\t\t\tThe uterus is 3\u201d long (in most non-pregnant women).\n\t\t\t<\/p>\n
This resource was created with funding and support from Eisai Inc. <\/em><\/p>\n<\/div>\n
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